| Registro completo |
| Provedor de dados: |
Biocell
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| País: |
Argentina
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| Título: |
Isolation of stem cells from adult rat kidneys
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| Autores: |
Gheisari,Yousof
Soleimani,Masoud
Zeinali,Sirous
Arefian,Ehsan
Atashi,Amir
Nikougoftar Zarif,Mahin
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| Data: |
2009-04-01
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| Ano: |
2009
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| Palavras-chave: |
Kidney failure
Regeneration
Cell differentiation
Renal replacement therapy
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| Resumo: |
The kidney has an inherent ability for recovery and regeneration following acute damage. However, there has been much contention as to the source of regenerating renal cells. The aim of this study was to isolate and characterize these cells. Normal rat kidneys were minced and cells were isolated with collagenase I and were cultured in an expansion medium. Adherent cells were isolated and expanded for more than 120 days in vitro. These cells had the potential of translineage differentiation into neural cells, adipocytes and osteocytes. These cells also expressed Nucleostemin, Cyclin D1, Notch1 and Survivin which are commonly expressed in stem cells. The results of the current work show that the adult kidney contains a population of multipotent stem cells.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452009000100004
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| Editor: |
Sociedad Latinoamericana de Microscopía Electrónica.; Centro Regional de Investigaciones Científicas y Tecnológicas (Mendoza, Argentina)
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| Formato: |
text/html
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| Fonte: |
Biocell v.33 n.1 2009
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| Direitos: |
info:eu-repo/semantics/openAccess
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